1. Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, Medical Sciences Building, Cincinnati, OH 45267, USA;2. Perinatal Institute, Cincinnati Children’s Research Foundation and Department of Pediatrics, College of Medicine, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA;3. Departments of Chemical and Biological Engineering and Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA;4. Departments of Biology and Biomedical Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA