Comparison of the protective ability of O and K immunity in mice after immunization withEscherichia coli |
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Authors: | Staffan Ahlsted Eva Jerning Bertil Kaijser |
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Institution: | (1) Institute of Medical Microbiology, Department of Clinical Bacteriology, University of Göteborg, Guldhedsgatan 10, S-413 46 Göteborg, Sweden;(2) Research and Development Laboratories, ASTRA Läkemedel AB, S-151 85 Södertälje, Sweden |
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Abstract: | The protective abilities ofEscherichia coli O and K immunity against intraperitoneal infection was compared in CBA mice immunized with formalin-killed bacteria. The K13 immunity achieved seemed somewhat more effective than the O6 immunity. This was also reflected in a slightly more rapid clearance of a liveE. coli O6K13 bacteria in K13-immunized animals than in those immunized with O6. However, the protection achieved afterE. coli O6K2 and O2K1 immunization was related more to O immunity than to K immunity. |
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