Volatile Oils from the Aerial Parts of Eremophila maculata and Their Antimicrobial Activity |
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| Authors: | Fadia S. Youssef Razan Hamoud Mohamed L. Ashour Abdel Nasser Singab Michael Wink |
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| Affiliation: | 1. Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566‐Cairo, Egypt;2. Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer, Feld 364, D‐69120, Heidelberg, (phone: +49‐6221‐544880;3. fax: +49‐6221‐544884) |
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| Abstract: | ![]()
The essential oils isolated from the fresh flowers, fresh leaves, and both fresh and air‐dried stems of Eremophila maculata (Scrophulariaceae) were characterized by GC‐FID and GC/MS analyses. Sabinene was the major component in most of the oils, followed by limonene, α‐pinene, benzaldehyde, (Z)‐β‐ocimene, and spathulenol. The leaf and flower essential oils showed antibacterial and antifungal activity against five Gram‐positive and four Gram‐negative bacterial strains, multi‐resistant clinical isolates from patients, i.e., methicillin‐resistant Staphylococcus aureus (MRSA), as well as two yeasts. Minimum inhibitory concentrations (MICs) and minimum microbicidal concentrations (MMCs) were between 0.25 and 4 mg/ml. |
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| Keywords: | Eremophila maculata Essential oils Sabinene Antimicrobial activity |
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