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11β-Hydroxylation of norethisterone acetate by Curvularia lunata
Authors:P Chosson  H Vidal  A Aumelas  F Couderc
Institution:Sanofi Elf-Biorecherches, Labège, France;Sanofi Recherche, Montpellier, France;C.C.I.P.E.Montpellier, France;Sanofi Recherche, Toulouse, France
Abstract:Abstract: The biotransformation of norethisterone acetate by Curvularia lunata was studied. The 11β-hydroxy-norethisterone acetate produced was identified by mass spectrometry, and 1H and 13C nuclear magnetic resonance after extractive sample preparation.
Keywords:Biotransformation  Norethisterone acetate              Curvularia lunata
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