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Oxamides as novel NR2B selective NMDA receptor antagonists |
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| Authors: | Barta-Szalai Gizella Borza István Bozó Eva Kiss Csilla Agai Béla Proszenyák Agnes Keseru György M Gere Anikó Kolok Sándor Galgóczy Kornél Horváth Csilla Farkas Sándor Domány György |
| Affiliation: | Gedeon Richter Ltd, 10, PO Box 27, H-1475 Budapest, Hungary. |
| Abstract: | A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test. |
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