Genetic localization of Hao-1, blind-sterile (bs), and Emv-13 on mouse chromosome 2. |
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| Authors: | S E Spence D J Gilbert B S Harris M T Davisson N G Copeland N A Jenkins |
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| Institution: | ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Maryland 21702. |
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| Abstract: | The blind-sterile (bs) mutation in the mouse was localized on Chromosome 2 between Hao-1 and Emv-13. N2 progeny from a backcross between congenic female 129.AKR-bs Emv-13 mice and (129.AKR-bs/bs x Mus musculus molossinus) F1 male mice were typed by analysis of isozyme variants for Hao-1, visible inspection for bs, and restriction fragment length polymorphism for Emv-13 and Emv-15. Comparison between markers on mouse Chromosome 2 and corresponding markers on human chromosomes suggest that the human homolog of bs will be located on 20q11-q13. |
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