The transition of the thick ascending limb of Henle's loop into the distal convoluted tubule in the nephron of the rat kidney |
| |
Authors: | Dr Brigitte Kaissling Stephan Peter Wilhelm Kriz |
| |
Institution: | (1) Anatomisches Institut der Universität Heidelberg, Federal Republic of Germany;(2) Anatomisches Institut, Im Neuenheimer Feld 307, 1 Heidelberg, Federal Republic of Germany |
| |
Abstract: | Summary Examination of serial semithin sections of rat kidney cortex and a subsequent electron microscopic study of selected areas revealed that the characteristic epithelium of the cortical part of the thick ascending limb of Henle extends for a varying distance beyond the macula densa. The transition from the relatively thin epithelium of the thick ascending limb at this site to the three -or even four-fold thicker epithelium of the convoluted part of the distal tubule is sharply defined and occurs without the interposition of an intermediate cell type.The position of the macula densa at the end but still clearly within the ascending limb of Henle's loop is functionally interpreted to guarantee the separation of the sensor point macula densa from disturbing influences which might arise from the secretory activity of the subsequent tubular portion.Investigations supported by the Deutsche Forschungsgemeinschaft. The skillful technical assistance of Mrs. Saliha Sabanovic is gratefully acknowledged |
| |
Keywords: | Rat kidney Thick ascending limb of Henle's loop Macula densa Distal convoluted tubule |
本文献已被 SpringerLink 等数据库收录! |