PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2 |
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Authors: | Erttmann Saskia F Bast Antje Seidel Julia Breitbach Katrin Walther Reinhard Steinmetz Ivo |
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Affiliation: | a Friedrich Loeffler Institute of Medical Microbiology, Ernst Moritz Arndt University of Greifswald, 17475 Greifswald, Germanyb Department of Medical Biochemistry and Molecular Biology, Ernst Moritz Arndt University of Greifswald, 17475 Greifswald, Germany |
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Abstract: | |
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Keywords: | AACOCF3, arachidonyl trifluoromethyl ketone AC, adenylate cyclase AGC, cAMP-dependent protein kinase A/protein kinase G/protein kinase C BMM, bone marrow-derived macrophages CAPE, caffeic acid phenethyl ester COX, cyclooxygenase cPLA2, cytosolic phospholipase A2 CREB, cAMP response element-binding protein Epac, exchange protein directly activated by cAMP IBMX, 3-isobutyl-1-methylxanthine IFN-γ, interferon-γ iNOS, inducible nitric oxide synthase JAK2, Januskinase 2 Keap-1, Kelch-like ECH-associated protein 1 L-NIL, L-N6-(1-iminoethyl)lysine dihydrochloride LPS, lipopolysaccharide MAFP, methyl arachidonyl fluorophosphonate MAPK, mitogen-activated protein kinase Nrf2, nuclear erythroid-derived 2p45-related factor 2 PG, prostaglandin PKA, protein kinase A PPAR, peroxisome proliferator-activated receptor Prx, peroxiredoxin RPLP0, ribosomal protein large P0 sulforaphane, 1-isothiocyanato-4-(methylsulfinyl) butane tBHQ, tert-butylhydroquinone |
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