PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2

Authors:	Erttmann Saskia F Bast Antje Seidel Julia Breitbach Katrin Walther Reinhard Steinmetz Ivo

Institution:	^a Friedrich Loeffler Institute of Medical Microbiology, Ernst Moritz Arndt University of Greifswald, 17475 Greifswald, Germany ^b Department of Medical Biochemistry and Molecular Biology, Ernst Moritz Arndt University of Greifswald, 17475 Greifswald, Germany

Abstract:

Keywords:	AACOCF3 arachidonyl trifluoromethyl ketone AC adenylate cyclase AGC cAMP-dependent protein kinase A/protein kinase G/protein kinase C BMM bone marrow-derived macrophages CAPE caffeic acid phenethyl ester COX cyclooxygenase cPLA₂ cytosolic phospholipase A₂ CREB cAMP response element-binding protein Epac exchange protein directly activated by cAMP IBMX 3-isobutyl-1-methylxanthine IFN-γ interferon-γ iNOS inducible nitric oxide synthase JAK2 Januskinase 2 Keap-1 Kelch-like ECH-associated protein 1 L-NIL L-N⁶-(1-iminoethyl)lysine dihydrochloride LPS lipopolysaccharide MAFP methyl arachidonyl fluorophosphonate MAPK mitogen-activated protein kinase Nrf2 nuclear erythroid-derived 2p45-related factor 2 PG prostaglandin PKA protein kinase A PPAR peroxisome proliferator-activated receptor Prx peroxiredoxin RPLP0 ribosomal protein large P0 sulforaphane 1-isothiocyanato-4-(methylsulfinyl) butane tBHQ tert-butylhydroquinone
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