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Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta)
Authors:Eugene H. Johnson  Susan E. Morgenstern  Jill M. Perham  Stephen W. Barthold
Abstract:Abstract: A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.
Keywords:rhesus macaque  colonic adenocarcinoma  endometriosis  CA-125
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