The Essential Oil Compositions of Ocimum basilicum from Three Different Regions: Nepal,Tajikistan, and Yemen |
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| Authors: | Farukh S Sharopov Prabodh Satyal Nasser A Awadh Ali Suraj Pokharel Hanjing Zhang Michael Wink Muhammadsho A Kukaniev William N Setzer |
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| Institution: | 1. Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, DE‐69120 Heidelberg;2. Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA, (phone: +1‐256‐824‐6519;3. fax: +1‐256‐824‐6519);4. Pharmacognosy Department, Faculty of Pharmacy, Sana'a University, P.O. Box 13150, Sana'a, Yemen;5. Pharmacognosy Department, Faculty of Clinical Pharmacy, Albaha University, Al Baha, KSA;6. V.?I. Nikitin Institute of Chemistry, Tajik Academy of Sciences, Ainy St. 299/2, Dushanbe, 734063, Tajikistan |
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| Abstract: | The aerial parts of Ocimum basilicum L. were collected from four different geographical locations, Sindhuli and Biratnagar (Nepal), Chormaghzak village (Tajikistan), and Sana'a (Yemen). The essential oils were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. A cluster analysis of 179 essential oil compositions revealed six major chemotypes: Linalool, eugenol, estragole, methyl eugenol, 1,8‐cineole, and geraniol. All four of the basil oils in this study were of the linalool‐rich variety. Some of the basil oils were screened for bioactivity including antimicrobial, cytotoxicity in human cancer cells, brine shrimp lethality, nematicidal, larvicidal, insecticidal, and antioxidant. The basil oils in this study were not notably antibacterial, cytotoxic, antioxidant, nor nematicidal, but were active in the brine shrimp lethality test, and did show larvicidal and insecticidal activities. |
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| Keywords: | Basil oil Antimicrobial activity Insecticidal activity Larvicidal activity Chemotaxonomy |
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