Natural killer cells and autoimmunity |
| |
| Authors: | Anthony R French and Wayne M Yokoyama |
| |
| Affiliation: | (1) Division of Pediatric Rheumatology, Department pf Pediatrics, Washington University School of Medicine, St Louis, MO, USA;(2) Howard Hughes Medical Institute, Division of Rheumatology, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA; |
| |
| Abstract: | ![]()
Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppressing autoimmunity. This review focuses on recent research elucidating a potential immunoregulatory role for NK cells in modulating T and B cell-mediated autoimmunity. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
