Proteome analysis of 5-fluorouracil-resistance-associated protein in human gastric cancer cells |
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| Authors: | Saeyoung Park Mina Lee Hae-Yeong Kim Doo-Il Jeoung |
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| Affiliation: | (1) In2Gen Company, Seoul, 110-799, Korea;(2) Plant Metabolism Research Center and Graduate School of Biotechnology, Kyung Hee University, Suwon, 449-701, Korea |
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| Abstract: | To identify proteins associated with 5-fluorouracil-resistance, a comparative proteome analysis was carried out using human gastric cancer cells and their derivative cells made resistant to 5-fluorouracil. Five proteins, a heterogeneous nuclear ribonucleoprotein K, transcription factor II, FLJ11122, hook3 protein and T-complex locus TCP-1, were identified that were differentially expressed in these cell lines. |
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| Keywords: | 2D-PAGE 5-fluorouracil gastric cancer cells proteome analysis |
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