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Crystal Structure of the Human Cannabinoid Receptor CB2
Authors:Xiaoting Li  Tian Hua  Kiran Vemuri  Jo-Hao Ho  Yiran Wu  Lijie Wu  Petr Popov  Othman Benchama  Nikolai Zvonok  K’ara Locke  Lu Qu  Gye Won Han  Malliga R Iyer  Resat Cinar  Nathan J Coffey  Jingjing Wang  Meng Wu  Vsevolod Katritch  Zhi-Jie Liu
Institution:1. iHuman Institute, ShanghaiTech University, Shanghai 201210, China;2. School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China;3. Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Science, Chinese Academy of Sciences, Shanghai, China;4. University of the Chinese Academy of Sciences, Beijing 100049, China;5. Center for Drug Discovery, Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA;6. Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA;7. Department of Molecular Medicine, Scripps Research, Jupiter, FL 33458, USA;8. Department of Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA;9. Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD 20892, USA;10. Moscow Institute of Physics and Technology, Dolgoprudny, Russia
Abstract:
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  • Keywords:G-protein coupled receptor  cannabinoid receptor CB2  crystal structure  ligand design  subtype selectivity
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