1.Protein Design Group,Centro Nacional de Biotecnología (CNB-CSIC),Cantoblanco,Madrid,Spain;2.Department of Immunology and Oncology,Centro Nacional de Biotecnología (CNB-CSIC),Cantoblanco,Spain
Abstract:
Background
The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) domain. The aim of this study is to characterize the family at the sequence level.