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Grand challenge commentary: Accessing new chemical space for 'undruggable' targets
Authors:Dandapani Sivaraman  Marcaurelle Lisa A
Affiliation:Chemical Biology Platform, Broad Institute, Cambridge, Massachusetts, USA. sivaram@broadinstitute.org
Abstract:The synthesis and biological annotation of small molecules from underexplored chemical space will play a central role in the development of drugs for challenging targets currently being identified in frontier areas of biological research such as human genetics.
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