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Protein S‐Nitrosylation in plants: Current progresses and challenges
Authors:Jian Feng  Lichao Chen  Jianru Zuo
Institution:1.Sainsbury Laboratory, University of Cambridge, Cambridge CB2 1LR, UK;2.State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, CAS Center for Excellence in Molecular Plant Sciences, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China;3.The University of Chinese Academy of Sciences, Beijing 100049, China;Correspondence:; Email: Jianru Zuo (jrzuo@genetics.ac.cn)
Abstract:Nitric oxide(NO) is an important signaling molecule regulating diverse biological processes in all living organisms. A major physiological function of NO is executed via protein S-nitrosylation, a redox-based the past decade, significant progress has been made in functional characterization of S-nitrosylated proteins Inviteposttranslational modification by covalently adding a NO molecule to a reactive cysteine thiol of a target protein.S-nitrosylation is an evolutionarily conserved mechanism modulating multiple aspects of cellular signaling. Duringin plants. Emerging evidence indicates that protein Snitrosylation is ubiquitously involved in the regulation of plant development and stress responses. Here we review current understanding on the regulatory mechanisms of protein S-nitrosylation in various biological processes in plants and highlight key challenges in this field.
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