Spontaneous adherence and rosette formation of lymphocytes to Leydig cells: an in vitro technique |
| |
| Authors: | A Rivenzon M Rivenzon R E Madden |
| |
| Institution: | Department of Surgery, New York Medical College and the Cooke Institute of Allergy, Roosevelt Hospital, New York, New York, U.S.A. |
| |
| Abstract: | A spontaneous rosette phenomenon occurs in vitro when suspensions of mouse testicular cells are mixed with suspensions of lymphocytes. The core cell of these rosettes are the Leydig cells, and the coronas are formed by lymphocytes. No other testicular cell, either seminal or Sertoli, participates in lymphocyte binding.Autogeneic, syngeneic, allogeneic, and xenogeneic lymphocytes from thymus, spleen, and peripheral blood similarly react with mouse Leydig cells. Lymphocytes from spleens of athymic nude mice and from chicken bursa also give Leydig rosettes. It is suggested that mouse Leydig cells carry membrane receptors spontaneously recognized by lymphocytes. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
