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Prevalence of integrons and a new dfrA17 variant in Gram‐negative bacilli which cause community‐acquired infections
Authors:Cemal Sandalli  Celal Kurtulus Buruk  Metin Sancaktar  Osman Birol Ozgumus
Institution:1. Microbiology & Molecular Biology Research Laboratory, Department of Biology, Faculty of Arts & Sciences, Rize University, 53100 Rize;2. Department of Medical Microbiology, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon;3. Clinical Microbiology Laboratory, 82nd Year of Government General Hospital, 53000 Rize;4. Department of Medical Microbiology, Faculty of Medicine, Rize University, 53100 Rize, Turkey
Abstract:A hundred and eleven Gram‐negative bacilli from community‐acquired infections were characterized by antimicrobial susceptibility testing, screened for class 1 and 2 integrons, and statistically evaluated for the association between antibiotic profile and the presence of integrons. The frequency with which integrons were harbored was 28.8%. Three E. coli strains contained a dfrA17 variant inserted in a class 1 integron. Results of PFGE indicated that some E. coli strains carrying integrons were clonally related. Carriage of gene cassettes was significantly associated with resistance to certain antibiotics (P < 0.05).
Keywords:community‐acquired infections  Gram‐negative bacilli  integrons
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