Health Outcomes of Gastric Bypass Patients Compared to Nonsurgical,Nonintervened Severely Obese |
| |
| Authors: | Ted D Adams Robert C Pendleton Michael B Strong Ronette L Kolotkin James M Walker E Sheldon Litwin Wael K Berjaoui Michael J LaMonte Tom V Cloward Erick Avelar Theophilus E Owan Robert T Nuttall Richard E Gress Ross D Crosby Paul N Hopkins Eliot A Brinton Wayne D Rosamond Gail A Wiebke Frank G Yanowitz Robert J Farney R Chad Halverson Steven C Simper Sherman C Smith Steven C Hunt |
| |
| Institution: | 1. Intermountain Health and Fitness Institute, Division of Cardiology, LDS Hospital, Salt Lake City, Utah, USA;2. Department of Internal Medicine, Division of General Medicine, University of Utah, Salt Lake City, Utah, USA;3. Department of Community and Family Medicine, Obesity and Quality of Life Consulting, Duke University Health System, Durham, North Carolina, USA;4. Intermountain Sleep Disorders Center, Division of Internal Medicine, LDS Hospital, Salt Lake City, Utah, USA;5. Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA;6. Department of Internal Medicine, Cardiology Division, University of Utah, Salt Lake City, Utah, USA;7. Department of Social and Preventive Medicine, SUNY at Buffalo, Buffalo, New York, USA;8. Division of Cardiology, University of Connecticut Health Center, Farmington, Connecticut, USA;9. Department of Internal Medicine, Cardiovascular Genetics Division, University of Utah, Salt Lake City, Utah, USA;10. Neuropsychiatric Research Institute, University of North Dakota School of Medicine, Fargo, North Dakota, USA;11. School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA;12. Huntsman Clinical Research Center, University of Utah, Salt Lake City, Utah, USA;13. Rocky Mountain Associated Physicians, Inc., Salt Lake City, Utah, USA |
| |
| Abstract: | Favorable health outcomes at 2 years postbariatric surgery have been reported. With exception of the Swedish Obesity Subjects (SOS) study, these studies have been surgical case series, comparison of surgery types, or surgery patients compared to subjects enrolled in planned nonsurgical intervention. This study measured gastric bypass effectiveness when compared to two separate severely obese groups not participating in designed weight‐loss intervention. Three groups of severely obese subjects (N = 1,156, BMI ≥ 35 kg/m2) were studied: gastric bypass subjects (n = 420), subjects seeking gastric bypass but did not have surgery (n = 415), and population‐based subjects not seeking surgery (n = 321). Participants were studied at baseline and 2 years. Quantitative outcome measures as well as prevalence, incidence, and resolution rates of categorical health outcome variables were determined. All quantitative variables (BMI, blood pressure, lipids, diabetes‐related variables, resting metabolic rate (RMR), sleep apnea, and health‐related quality of life) improved significantly in the gastric bypass group compared with each comparative group (all P < 0.0001, except for diastolic blood pressure and the short form (SF‐36) health survey mental component score at P < 0.01). Diabetes, dyslipidemia, and hypertension resolved much more frequently in the gastric bypass group than in the comparative groups (all P < 0.001). In the surgical group, beneficial changes of almost all quantitative variables correlated significantly with the decrease in BMI. We conclude that Roux‐en‐Y gastric bypass surgery when compared to severely obese groups not enrolled in planned weight‐loss intervention was highly effective for weight loss, improved health‐related quality of life, and resolution of major obesity‐associated complications measured at 2 years. |
| |
| Keywords: | |
|
|
