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Diet and bacterial colonization: role of probiotics and prebiotics
Authors:WAllan Walker  Linda C Duffy
Institution:

a Harvard Medical School Combined Program Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Children’s Hospital, Boston, MA USA

* Department of Pediatrics, Children’s Hospital of Buffalo, School of Medicine and Biomedical Sciences (SUNY), Buffalo, NY USA

Abstract:The intestinal mucosa functions as a defensive barrier that limits dietary antigen transport and microbial pathogens from colonizing enterocytes. The potential role of lactic acid bacteria, specifically Bifidobacteria, in probiotic and prebiotic functional food supplements is reviewed in the context of bacterial colonization, adherence, and disease prevention. This article reviews the mechanisms of action and optimization of methods that will lead to a new generation of biotic products with enhanced biologic properties and well-being foods.
Keywords:Bifidobacteria  Lactobacilli  prebiotics  probiotics  intestinal colonization  adhesion
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