Detection of biologically active substances with antagonistic and stimulating activity in Spirulina platensis

The results of studies on the detection of biologically active substances (BAS) in biomass dilutions and culture fluid of Spirulina platensi and algae (Chlorella, Fucus, Laminaria) by the agar diffusion method are presented. After the sterilization of the solutions with chloroform (CF) a substance with lysozyme-like activity and 2 substances with antagonistic activity deep in agar and on its surface were detected with the use of the micrococcal indicator strain. After CF treatment, depending on the concentration of S. platensis strains, a compound stimulating the growth of bacteria and sensitive to heat treatment was detected. BAS were also detected with the use of other indicator cultures.