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Cutaneous and Mucosal Phaeohyphomycosis Caused by Exophiala spinifera in a Pregnant Patient: Case Report and Literature Review |
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| Authors: | Le Wang Xiaodong She Guixia Lv Yongnian Shen Qing Cai Rong Zeng Caixia Li Yiping Ge Shuwen Deng G S de Hoog Min Li Weida Liu |
| Institution: | 1. Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, No. 12, Jiang Wangmiao street, Nanjing, 210042, People’s Republic of China 2. Shanghai Institute of Medical Mycology, Changzheng Hospital, Second Military Medical University, Shanghai, People’s Republic of China 3. Centraalbureau voor Schimmelcultures Fungal Biodiversity Centre, Utrecht, The Netherlands |
| Abstract: | We report a case of mucocutaneous phaeohyphomycosis caused by Exophiala spinifera. Crusty plaques and nodules were major clinical features. Histological examination revealed brown yeast-like cells and hyphae. Mycological and molecular data identified E. spinifera as etiologic agent. Oral itraconazole was effective, which was in accordance with the results of in vitro susceptibility testing. We speculated that her pregnancy may play a role of risk factor in the infection by E. spinifera. |
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