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Osteoporosis Treatment After Osteoporotic Fractures: Data From a Single Medical Center
Institution:1. Endocrine Institute, Meir Medical Center, Kfar Saba, Israel;2. Orthopedic Department, Meir Medical Center, Kfar Saba, Israel;3. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Abstract:ObjectiveMost patients do not receive osteoporosis treatment after osteoporotic fracture. This study reviewed osteoporosis treatment after osteoporotic fractures in a center without a Fracture Liaison Service.MethodsWe identified all patients with hip, vertebral, humeral or radial fractures, evaluated in Meir Medical Center, in 2017. The exclusion criteria were not a Clalit Health Services member, high-energy fracture or 30-day postoperative mortality. The primary endpoint was osteoporosis drugs issued within 12 months of fracture. Secondary endpoints included bone densitometry and 1-year mortality.ResultsFive-hundred-eighty-two patients (average age 78.6 ± 11.1 years, 75.8% women) were included. There were 321 (55.5%) hip, 84 (14.1%) humeral, 33 (5.6%) vertebral, and 144 (24.7%) radial fractures. Osteoporosis drugs were issued to 26.5% of the patients; those with humeral fractures received the least (21.4%) and vertebral, the most (30.3%; P = .51). Bone densitometry was performed in 23.2% of patients. One-year mortality after hip fracture was 12.1%, followed by humeral (3.6%; P < .05). Logistic regression showed that previous treatment (odds ratio OR] = 7.4; 95% confidence interval CI] 3.6–15.2), bone densitometry (OR = 4.4; 95% CI 2.6–7.4) and endocrinology visit (OR = 2.6; 95% CI, 1.4–4.6) were the most important factors associated with treatment.ConclusionFewer than one third of patients received pharmacotherapy within 1 year after fracture. Because pharmacotherapy reduces future fractures and mortality, we recommend that medical staff who care for patients with fracture adopt practical and effective strategies to increase treatment rates among patients with osteoporotic fractures.
Keywords:osteoporosis  osteoporotic fractures  secondary fracture prevention  hip fracture  CHS"}  {"#name":"keyword"  "$":{"id":"kwrd0030bb"}  "$$":[{"#name":"text"  "_":"Clalit Health Services  CI"}  {"#name":"keyword"  "$":{"id":"kwrd0030ddd"}  "$$":[{"#name":"text"  "_":"confidence interval  FLS"}  {"#name":"keyword"  "$":{"id":"kwrd0030ff"}  "$$":[{"#name":"text"  "_":"Fracture Liaison Service  HMO"}  {"#name":"keyword"  "$":{"id":"kwrd003hhh"}  "$$":[{"#name":"text"  "_":"health maintenance organization  MMC"}  {"#name":"keyword"  "$":{"id":"kwrd0030jjj"}  "$$":[{"#name":"text"  "_":"Meir Medical Center  OR"}  {"#name":"keyword"  "$":{"id":"kwrd003ll0"}  "$$":[{"#name":"text"  "_":"odds ratio
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