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Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption
Institution:1. Department of Orthopaedic Surgery in Sir Run Run Shaw Hospital, Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China;2. Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, Hangzhou, China;3. Kidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China;4. Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou 310058, China;5. Department of Biophysics, Zhejiang University School of Medicine, Hangzhou 310058, China
Abstract:
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  • Keywords:gasdermin D  tissue homeostasis  osteoclast  lysosome  endosome
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