马方综合征并发感染性心内膜炎的外科治疗体会

目的：探讨马方综合征并发感染性心内膜炎的外科治疗的体会。方法：回顾性分析2009年7月至2012年12月我院30例马方综合征并发感染性心内膜炎患者，男19例，女11例，年龄23.58（41．6±15．2）岁，所有患者均进行了抗生素治疗和心瓣膜置换或成形术，其中对患者进行经典Bent,all手术12例，纽扣法Bentall手术18例，比较分析手术治疗马方综合征并发感染性心内膜炎疗效。结果：手术时间276．742（405．0±125．0）min，体外循环时间115—319（159．0±43．0）rain，机械通气辅助时间1～12（2．4±2．0）d．住院时间10．60（28．5±11．0）d，术后出现并发症有7例，经二期手术治愈有5例，2例抢救无效死亡，并发症发生率为23.3％，死亡率为6．7％。结论：对于马方综合征并发感染性心内膜炎患者，正确把握手术的时机和抗感染药物治疗剂量，积极采取外科手术治疗是最佳的治疗方法。

Surgical Treatment Experience of Infective Endocarditis in Marfan Syndrome

Objective： To discuss the Surgical treatment experience of infective endocarditis in Marfan syndrome. Methods： In 2009 July to December 2012, 30 patients with concurrent Malaysia syndrome and infective endocarditis, （19 male and female in 11 cases, aged 23-58 （41.6：1： 15.2） were treated and retrospectively analyze. Bentall surgery on the patients with antibiotic therapy and heart valve replacement or plasty, analysis of surgical treatment for Malaysia syndrome complicated with infective endocarditis were compared and analyzed. Results： Operating time was 276-742 （405.0± 125.0）min; CPBT was 115-319 （ 159.0± 43.0）min; mechanical ventilation as- sist time was 1-12 （2.4± 2.0）d; length of stay was 10-0 （28.5 ± 11.0）d. Seven patients after surgery had complications; patients cured by thesecond surgery were 5 cases, death of rescue were invalid in2 cases. The incidences of complications and mortality were 23.3% and 6.7%, respectively. Coneinsion： For infective endocarditis in Marfan syndrome, taking surgical treatment is the best treatment method with grasping the correctly operation timing and anti-infection drug treatment.