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Biophysical and biorheological studies on the precursor cells at different stages
Authors:Jinhua Wang  Dagong Sun  Weijuan Yao  Zhu Zeng  Zongyi Yan and Zongyao Wen
Abstract:Splenic erythroblasts were obtained from mice during the acute disease caused by anemia-inducing virus (FVA). They were cultured in a medium containing EPO, BSA and so on. We studied their biomechanical and hemorheological behavior after 12 h, 24 h and 48 h. The results showed obvious changes in their electrophoretic mobility, osmotic fragility, membrane fluidity and membrane viscoelastic properties with the development of erythroblast. The changes were associated with the interactions of the protein and lipid and the elements of the membrane.
Keywords:precursor cell  electrophoretic mobility  osmotic fragility  membrane fluidity  membrane viscoelastic properties
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