Distribution of 1,25-Dihydroxyvitamin D3 Receptor Immunoreactivity in the Rat Olfactory System |
| |
| Authors: | Sirit D. Glaser Timothy D. Veenstra Gustav F. Jirikowski Kirsten Prüfer |
| |
| Affiliation: | (1) Institut für Anatomie II, Friedrich-Schiller Universität Jena, D-07740 Jena, Teichgraben 7, Germany;(2) Nephrology Research Unit, Department of Medicine and Biochemistry and Molecular Biology, Mayo Clinic/Foundation, Rochester, Minnesota, 55905 |
| |
| Abstract: | 1.The rat olfactory system contains numerous target sites for 1,25-dihydroxyvitamin D3, as determined by receptor protein (VDR) immunocytochemistry and in situ hybidization.2.Nuclear and cytoplasmic VDR immunoreactivity as well as the corresponding hybridization signal was observed in neurons in the olfactory epithelium, the olfactory bulb, and throughout the limbic system in locations also known to be glucocorticoid targets.3.The widespread distribution of VDR indicates the distinct functional importance of 1,25-dihydroxyvitamin D3 for olfactory perception. |
| |
| Keywords: | 1,25-dihydroxyvitamin D3 olfactory system male rat vitamin D receptor reproduction |
| 本文献已被 SpringerLink 等数据库收录！ |
|
