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Aquaporin-6 is expressed along the rat gastrointestinal tract and upregulated by feeding in the small intestine |
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| Authors: | Umberto Laforenza Giulia Gastaldi Mariarosa Polimeni Simona Tritto Marisa Tosco Ulderico Ventura Manuela F Scaffino Masato Yasui |
| Institution: | 1. Department of Physiology, Section of Human Physiology, University of Pavia, Via Forlanini 6, 27100, Pavia, Italy 2. Department of Experimental Medicine, Section of Normal Human Anatomy, University of Pavia, Via Forlanini 6, 27100, Pavia, Italy 3. Department of Biomolecular Sciences and Biotechnologies, University of Milan, Via Celoria 26, Milano, Italy 4. Department of Pharmacology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan |
| Abstract: | BackgroundSeveral aquaporins (a family of integral membrane proteins) have been recently identified in the mammalian gastrointestinal tract, and their involvement in the movement of fluid and small solutes has been suggested. In this direction we investigated, in some regions of the rat gastrointestinal tract, the presence and localization of aquaporin-6, given its peculiar function as an ion selective channel. |
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