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Geminiviruses: a tale of a plasmid becoming a virus
Authors:Mart Krupovic  Janne J Ravantti  Dennis H Bamford
Institution:(1) Department of Biological and Environmental Sciences and Institute of Biotechnology, Biocenter 2, University of Helsinki, Viikinkaari 5, P.O. Box 56, FIN-00014 Helsinki, Finland
Abstract:

Background  

Geminiviruses (family Geminiviridae) are small single-stranded (ss) DNA viruses infecting plants. Their virion morphology is unique in the known viral world – two incomplete T = 1 icosahedra are joined together to form twinned particles. Geminiviruses utilize a rolling-circle mode to replicate their genomes. A limited sequence similarity between the three conserved motifs of the rolling-circle replication initiation proteins (RCR Reps) of geminiviruses and plasmids of Gram-positive bacteria allowed Koonin and Ilyina to propose that geminiviruses descend from bacterial replicons.
Keywords:
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