| 耗竭性游泳对大鼠心肌线粒体膜功能的影响 |
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| 引用本文： | 王文信,丁树哲.耗竭性游泳对大鼠心肌线粒体膜功能的影响[J].生物化学与生物物理学报,1994,26(2):243-246. |
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| 作者姓名： | 王文信 丁树哲 |
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| 作者单位： | 华东师范大学体育系运动生化实验室，安徽省体育科学研究所运动医学研究室 |
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| 摘 要： | 耗竭性游泳对大鼠心肌线粒体膜功能的影响王文信，丁树哲，许豪文（华东师范大学体育系运动生化实验室，上海２０００６２）关键词心肌线粒体，内膜表面电位，游离钙，总钙，合成活力长时间耗竭性游泳或跑步引起心肌、骨骼肌、肝脏等线粒体结构和功能变化，这些变化可能与...
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| 关 键 词： | 心肌 线粒体 游离钙 总钙 钙 |
Effects of Exercise on the Rat Heart Mitochondrial Membrane Function |
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| WANG Wen-Xin,DING Shu-Zhe and XU Hao-Wen.Effects of Exercise on the Rat Heart Mitochondrial Membrane Function[J].Acta Biochimica et Biophysica Sinica,1994,26(2):243-246. |
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| Authors: | WANG Wen-Xin DING Shu-Zhe and XU Hao-Wen |
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| Abstract: | Rats were used as an experimental model of exercise in exhausting swimming.Heart mitochondrial malonialdehyde (MDA) contents were observed with TBA reaction. Heart mitochondrial membrane surface potential were determined with the fluoresenoe technique using 1, 8-ANS as a probe. Mitoehondrial free Ca2+ were investigated with the fluoresence technique using Fura-2 AM as the Ca2+ indicator.Mitochondrial total Ca2+ contents were observed with atomic absorption spectro scopy. Eeart mitochondrial ATP synthesis activity were determined with bioluminesence method. After exhausting swimming, mitochondrial MDA were eignificantly elevated. Mitochondrial membrane surface potential and mitochondrial free Ca2+ were signifieantly decreased. Mitochondrial total Ca2+ contents were significantly increased. Heart mitochondrial ATP synthesis activity were significantly depressed. |
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