Effect of (--)-hydroxycitrate on ipomeamarone biosynthesis from pyruvate in sweet potato with black rot

(—)-Hydroxycitrate, a potent inhibitor of ATP: citrateoxaloacetate-lyase inhibited about 90% and 30% respectively,of the conversion of citrate-1,5^-14C and pyruvate-3^-14C intoipomeamarone, in sweer potato root tissuw infected with Ceratocystisfimbriota. However, the conversion of acetate-2¹⁴C into ipomeamaronewas not affected by (—)-hydroxycitrate. These resultssuggest that ATP: citrate oxaloacetate lyase plays a role inthe supply of acetyl CoA for terpenoid formation. ¹This paper constitutes part 109 of the Phytopathological Chemistryof Sweet Potato with Black Rot and Injury. (Received July 29, 1973; )