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Distribution of NG, NG-dimethylarginine in nuclear protein fractions |
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| Authors: | LC Boffa J Karn G Vidali VG Allfrey |
| Institution: | The Rockefeller University, New York, N.Y. 10021, USA |
| Abstract: | Nuclear proteins have been fractionated into five distinct classes according to their extractability from rat liver nuclei at different pH and salt concentrations. The fractions have been analyzed for their amino acid composition which shows the presence of NG, NG-dimethylarginine, in sizable amount, in non-histone nuclear proteins (NHNP). This modification is most prominent in proteins which are found associated with rapidly-labeled heterogeneous RNA (HnRNP proteins). |
| Keywords: | NHNP non-histone nuclear proteins HnRNP proteins nuclear proteins associated with HnRNA in 40S particles HnRNA rapidly-labeled heterogeneous nuclear RNA PMSF phenylmethylsulfonyl fluoride |
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