ACTL6a Enforces the Epidermal Progenitor State by Suppressing SWI/SNF-Dependent Induction of KLF4期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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ACTL6a Enforces the Epidermal Progenitor State by Suppressing SWI/SNF-Dependent Induction of KLF4

Authors:	Xiaomin Bao Jiong Tang Vanessa Lopez-Pajares Shiying Tao Kun Qu Gerald R Crabtree Paul A Khavari

Institution:	1. Program in Epithelial Biology, Stanford University, Stanford, CA 94305, USA;2. Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA;3. Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA

Abstract:	Download : Download high-res image (200KB) Download : Download full-size image Highlights? ACTL6a is downregulated during epidermal differentiation ? ACTL6a loss in epidermis causes progenitor loss and terminal differentiation ? ACTL6a is required for repression of KLF4 and other epidermal differentiation genes ? ACTL6a prevents binding of the SWI/SNF complex to differentiation genes

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