Acute GIycemic Control in Hospitalized Patients: Evidence Published Since the American College of Endocrinology Position Statement |
| |
| Institution: | 1. White Plains Hospital, White Plains, NY;2. White Plains Hospital, White Plains, NY;1. Department of Emergency Medicine, Vanderbilt University School of Medicine, 1313 21st Ave, Nashville, TN 37232;2. Section of Hospital Medicine, Division of General Internal Medicine and Public Health, Center for Clinical Quality and Implementation Research, Vanderbilt University School of Medicine, 1313 21st Ave, Nashville, TN 37232;3. Department of Emergency Medicine, Vanderbilt University School of Medicine, 1313 21st Ave, Nashville, TN 37232;4. Department of Biostatistics, Vanderbilt University School of Medicine, 1313 21st Ave, Nashville, TN 37232;5. Departments of Medicine and Biostatistics, Division of General Internal Medicine and Public Health, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN;6. Geriatric Research, Education, and Clinical Center, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN;7. Departments of Biomedical Informatics and Medicine, Division of General Internal Medicine and Public Health, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN;8. Geriatric Research, Education, and Clinical Center, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN;9. Division of Cardiology, Vanderbilt University School of Medicine, Nashville, TN;10. Owen Graduate School of Management, Vanderbilt University, Nashville, TN;11. Department of Medicine, Institute for Medicine and Public Health, Vanderbilt University School of Medicine, Nashville, TN;12. Geriatric Research, Education, and Clinical Center, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN |
| |
| Abstract: | Background: In a 2004 position statement, the American College of Endocrinology (ACE) recommended that the plasma glucose level be ≤110 mg/dL (fasting) and <180 mg/dL (postprandial) for hospitalized patients not in the intensive care unit (ICU) and 80 to 110 mg/dL for hospitalized patients in the ICU, whether or not they had documented diabetes mellitus.Objective: This paper reviews published studies on this topic, with focus on those appearing after the ACE statement.Methods: Relevant studies were identified by a MEDLINE search of references and studies and by extensive familiarity with the topic.Results: The results of observational studies have been mixed and are complicated by uncertainty as to whether hyperglycemia is simply a marker of illness severity or is causally related to adverse clinical outcome.Conclusions: Intriguing evidence from randomized controlled trials suggests that tight glycemic control in the hospitalized patient improves mortality and morbidity, although the above-recommended glucose target values have not been met in some studies. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
