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Glycosylated nervogenic acid derivatives from Liparis condylobulbon (Reichb.f.) leaves
Authors:Tereza &#x;lapetov  Karel &#x;mejkal  Gabbriella Innocenti  Stefano Dall&#x;Acqua  Jrg Heilmann  Petr Babula  Eva Hamzov  Milan emli ka
Institution:aDepartment of Natural Drugs, University of Veterinary and Pharmaceutical Sciences Brno, Palackého 1-3, 612 42 Brno, Czech Republic;bDepartment of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35131 Padua, Italy;cFaculty of Chemistry and Pharmacy, University of Regensburg, Universitaetstrasse 31, 93053 Regensburg, Germany
Abstract:Three new nervogenic acid glycosides, 1-O-α-l-rhamnopyranosyl 3,5-bis(3-methyl-but-2-enyl)-4-O-α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl]-benzoate, 3,5-bis(3-methyl-but-2-enyl)-4-O-α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl]-benzoic acid, and bis{3,5-bis(3-methyl-but-2-enyl)-4-O-α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl]-benzoyl} 1,2-O-β-d-glucopyranose, which we named condobulbosides A–C, were isolated from a methanol extract of the leaves of Liparis condylobulbon together with an apigenin C-glycoside, schaftoside. Their structures were established on the basis of spectral techniques, namely, UV, IR, HR-MS spectroscopy, both 1D and 2D NMR experiments, and chemical reactions.
Keywords:Liparis condylobulbon  Orchidaceae  Nervogenic acid  Glycosides
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