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A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics |
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| Authors: | Kyle M. Stiers Lesa J. Beamer |
| Affiliation: | 1. Biochemistry Department, University of Missouri, 117 Schweitzer Hall, Columbia, MO 65211, USA |
| Abstract: |  |
| Keywords: | missense variants inherited disease enzyme loop mobility X-ray crystallography molecular dynamics conformational ensemble |
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