| 老头草半仿生提取物的降血糖作用研究 |
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| 引用本文： | 方玉春,辛现良,朱伟明,顾谦群.老头草半仿生提取物的降血糖作用研究[J].天然产物研究与开发,2007,19(3):508-510. |
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| 作者姓名： | 方玉春 辛现良 朱伟明 顾谦群 |
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| 作者单位： | 教育部海洋药物重点实验室,中国海洋大学海洋药物研究所,青岛,266003 |
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| 摘 要： | 本文利用尾静脉注射四氧嘧啶90mg/kg致糖尿病小鼠模型,研究了老头草半仿生提取物(LSBE)的降血糖作用,测定了LSBE对正常和糖尿病模型小鼠的血糖(Glu)、胆固醇(Chol)、甘油三酯(TG)、血清胰岛素(Ins)和胰淀粉酶(Amy)的影响。结果显示LSBE可使正常及模型小鼠血糖明显降低,并发现治疗8d后四氧嘧啶模型小鼠Ins、TG升高,Amy降低。
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| 关 键 词： | 老头草 半仿生提取法 糖尿病 血糖 胰岛素 |
| 文章编号： | 1001-6880（2007）03-0508-03 |
| 收稿时间： | 2006-05-15 |
| 修稿时间： | 2006-05-152006-08-25 |
Effects of Semi-bionic Extract of Leontopodium leontopodiodes on Normal and Diabetic Mice |
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| FANG Yu-chun,XIN Xian-liang,ZHU Wei-ming,GU Qian-qun.Effects of Semi-bionic Extract of Leontopodium leontopodiodes on Normal and Diabetic Mice[J].Natural Product Research and Development,2007,19(3):508-510. |
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| Authors: | FANG Yu-chun XIN Xian-liang ZHU Wei-ming GU Qian-qun |
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| Institution: | Key Laboratory of Marine Drugs,Ministry of Education,Marlne Drug and Food Institute, Ocean University of China, Qingdao 266003, China |
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| Abstract: | Effects of semi-bioni extract of L.leontopodiodes(LSBE)on the blood glucose(Glu),triglyceride(TG),cholesterol(Chol)and pancreatic amylace of normal and diabetic mice induced by alloxan were studied.The results showed that the blood Glu,TG and insulin of alloxan-treated mice were increased significantly.LSBE could reduce the blood glucose of normal and alloxan-induced diabetic mice.But no observed effects of LSBE were found on blood TG,Chol and Amy of normal and diabetic mice. |
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| Keywords: | L leontopodiodes semi-bionic extraction diabetic blood glucose insulin |
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