Terahertz Time-Domain Spectroscopy of Glucose and Uric Acid |
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Authors: | P.C. Upadhya Y.C. Shen A.G. Davies E.H. Linfield |
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Affiliation: | (1) Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge, CB3 0HE, UK;(2) School of Electronic and Electrical Engineering, University of Leeds, Leeds, LS2 9JT, UK |
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Abstract: | ![]() We report the use ofterahertz time-domain spectroscopy for thestudy of two therapeutic bio-molecules:glucose and uric acid. Terahertztransmission spectra of crystalline samplesof both molecules were measured between 0.1–3.0 THz using an evacuated spectroscopysystem. We propose that the stereo-isomersof glucose show spectral featuresoriginating from intermolecular vibrationalmodes, as do uric acid and its derivativemolecule, allantoin. In addition, wepresent a full temperature dependence ofthe terahertz absorption of L-glucose. |
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Keywords: | Glucose intermolecular temperature dependent absorption terahertz time-domain spectroscopy uric acid |
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