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Terahertz Time-Domain Spectroscopy of Glucose and Uric Acid
Authors:P.C. Upadhya  Y.C. Shen  A.G. Davies  E.H. Linfield
Affiliation:(1) Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge, CB3 0HE, UK;(2) School of Electronic and Electrical Engineering, University of Leeds, Leeds, LS2 9JT, UK
Abstract:
We report the use ofterahertz time-domain spectroscopy for thestudy of two therapeutic bio-molecules:glucose and uric acid. Terahertztransmission spectra of crystalline samplesof both molecules were measured between 0.1–3.0 THz using an evacuated spectroscopysystem. We propose that the stereo-isomersof glucose show spectral featuresoriginating from intermolecular vibrationalmodes, as do uric acid and its derivativemolecule, allantoin. In addition, wepresent a full temperature dependence ofthe terahertz absorption of L-glucose.
Keywords:Glucose  intermolecular  temperature dependent absorption  terahertz  time-domain spectroscopy  uric acid
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