| Beige-Nude小鼠免疫学特性研究概况 |
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| 引用本文： | 马荣,毕明刚. Beige-Nude小鼠免疫学特性研究概况[J]. 中国实验动物学报, 2009, 17(6): 460-464 |
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| 作者姓名： | 马荣 毕明刚 |
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| 作者单位： | 1. 河北北方学院,张家口,075029;中国医学科学院药用植物研究所,北京,100193
2. 中国医学科学院药用植物研究所,北京,100193 |
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| 基金项目： | 国家科技部"十一五"支撑课题重点项目子课题 |
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| 摘 要： | 免疫缺陷动物是研究免疫相关疾病的良好动物模型。Beige-Nude小鼠是T淋巴细胞和NK细胞同时缺陷的小鼠,其T细胞和NK细胞活性很低,最初为肿瘤的研究而培育。从上世纪七十年代起,学者们对其免疫学特性进行了广泛而深入的研究,为其在其他领域的应用奠定了免疫学基础。
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| 关 键 词： | 免疫缺陷小鼠 T/NK缺陷 免疫学特性 |
Immunological Characteristics of Beige-Nude Mice:Research and Development |
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| MA Rong,BI Ming-gang. Immunological Characteristics of Beige-Nude Mice:Research and Development[J]. Acta Laboratorium Animalis Scientia Sinica, 2009, 17(6): 460-464 |
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| Authors: | MA Rong BI Ming-gang |
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| Affiliation: | 1.Hebei North University,Zhangjiakou 075029,China;2.The Institute of Medicinal Plant Development,Beijing 100193,China) |
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| Abstract: | Immunodeficient animals are animal models that are suitable for medical research. Beige-Nude mice are deficient in both T lymphocytes and natual killer (NK) cells simultaneously. The T cell activity and NK cell activity are much lower in Beige-Nude mice. They were bred for cancer research at first. Researchers have studied the immunologic characteristics of Beige-Nude mice vastly and deeply since 1970s. So this expands its application in medical research. |
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| Keywords: | Immunodeficient Mice Beige-Nude Immunologic characteristics |
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