The effect of the size of the irradiation field on the severity and outcome of the radiation injury of swine skin

Swine skin areas of 12.56 cm2, 50 cm2 and 100 cm2 were exposed to beta-particles from 90Sr + 90Y (100 Gy). The increase in size of the exposed site caused a considerable increase in the degree of the affection and a change in the regeneration rate. Epithelialization of 12.56 cm2 skin field was completed by the 14th-16th week, and it was absent after 4.5 years in the fields of 50 and 100 cm2.