HCCR-1, a novel oncogene,encodes a mitochondrial outer membrane protein and suppresses the UVC-induced apoptosis |
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| Authors: | Goang-Won Cho Seung Min Shin Hyun Kee Kim Seon-Ah Ha Sanghee Kim Joo-Hee Yoon Soo Young Hur Tae Eung Kim Jin Woo Kim |
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| Institution: | (1) Molecular Genetic Laboratory, College of Medicine, The Catholic University of Korea, Seoul, 137-040, Korea;(2) Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, 137-040, Korea |
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| Abstract: | Background The Human cervical cancer oncogene (HCCR-1) has been isolated as a human oncoprotein, and has shown strong tumorigenic features.
Its potential role in tumorigenesis may result from a negative regulation of the p53 tumor suppressor gene. |
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