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An Improved Method for the Preparation of 4-Cyano-2-butenyl-deoxyribonucleosidephosphoramidites |
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| Authors: | G. Duckworth J. Ackroyd |
| Affiliation: | Cruachem Ltd Todd Campus, West of Scotland Science Park , Acre Road, Glasgow, Scotland , G20 OUA |
| Abstract: | Abstract An improved alternative synthesis of 4-cyano-2-butenyldeoxy nucleosidephosphoramidites in > 100g quantities is described via reaction of the phosphordiamidites with 4-cyano-2-buten-1-ol. |
| Keywords: | |