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Oligodeoxyxylonucleotides Form Stable Triplexes with Single-Stranded DNA |
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| Authors: | M B Gottikh Y I Alekseev A V Perminov M D Pinskaya Z A Shabarova |
| Institution: | 1. Belozersky Institute of Physico-Chemical Biology, Moscow State University , Vorob'evy Hills, 119899, Moscow, RUSSIA;2. Belozersky Institute of Physico-Chemical Biology, Moscow State University , Vorob'evy Hills, 119899, Moscow, RUSSIA;3. Syntol Co. , Timiryazevskaya ul. 42, 127550, MOSCOW, RUSSIA |
| Abstract: | Abstract The ability of oligodeoxyxylopyrimidilates to form triplexes with complementary single-stranded DNA at the neutral pH was found. The complex composition, relative strand orientation and base-pairing scheme were determined using electromobility shift assay and thermal denaturation experiments. |
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