Oligonucleotide Synthesis on Linear Reactive Polymer Grafted onto Solid Support,Medical Diagnostics Applications |
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Authors: | C. Minard-basquin C. Chaix C. Pichot B. Mandrand |
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Affiliation: | UMR 103, Unité mixte CNRS/bioMérieux , ENS de Lyon, 69 364, Lyon cedex, 07 |
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Abstract: | Abstract A new strategy has been developed to obtain polymer-ODN conjugates. However, free ODN appeared to contaminate synthesis. Various hypotheses are described herein to explain this side reaction. |
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