Synaptic plasticity in an altered state |
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| Authors: | Philpot Benjamin D Bear Mark F |
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| Affiliation: | Howard Hughes Medical Institute, Department of Neuroscience, Brown University, Box 1953, Providence, RI 02912, USA. |
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| Abstract: | 
In this issue of Neuron, record from synaptically coupled pairs of CA3 neurons to closely examine the induction of synaptic depression at a small number of identified synapses. The authors provide convincing evidence that the activation history of a synapse determines both the ability of a synapse to depress and the mechanism of depression. |
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