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A phylogenetic group of Escherichia coli associated with active left-sided Inflammatory Bowel Disease |
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| Authors: | Andreas M Petersen Eva M Nielsen Eva Litrup Jørn Brynskov Hengameh Mirsepasi Karen A Krogfelt |
| Institution: | (1) Department of Gastroenterology, Hvidovre University Hospital, 2650 Hvidovre, DK, Denmark;(2) Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, 2300 Copenhagen S, DK, Denmark;(3) Department of Gastroenterology, Herlev University Hospital, 2730 Herlev, DK, Denmark |
| Abstract: | BackgroundEscherichia coli have been found in increased numbers in tissues from patients with Inflammatory Bowel Disease (IBD) and adherent-invasive E. coli have been found in resected ileum from patients with Crohn's disesae. This study aimed to characterize possible differences in phylogenetic group (triplex PCR), extraintestinal pathogenic E. coli (ExPEC) genes and multilocus sequence type (MLST) between E. coli strains isolated from IBD patients with past or present involvement of the left side of the colon and from controls. |
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