Three new geranyl aurones from the leaves of Artocarpus altilis |
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Authors: | Nguyen Thi Thanh Mai Nguyen Xuan Hai Dang Hoang Phu Phan Nguyen Huu Trong Nguyen Trung Nhan |
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Institution: | Faculty of Chemistry, University of Science, Vietnam National University – Hochiminh City, Viet Nam |
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Abstract: | From the MeOH extract of the leaves of Artocarpus altilis (Moraceae), three new aurones, altilisin H (1), I (2), and J (3), have been isolated together with two known flavonoids. Their structures were elucidated on the basis of spectroscopic data. All compounds possessed tyrosinase inhibitory activity with IC50 values less than 100 μM, while compounds 1–3 displayed potent α-glucosidase inhibitory activity with IC50 values ranging from 4.9 to 5.4 μM. |
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