Cytotoxic cycloartanes from the fruits of Caloncoba glauca |
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| Authors: | James D. Simo Mpetga Mathieu Tene Hippolyte K. Wabo Shi-Fei Li Ling-Mei Kong Hong-Ping He Xiao-Jiang Hao Pierre Tane |
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| Affiliation: | 1. Laboratory of Natural Products Chemistry, Department of Chemistry, University of Dschang, P.O. Box 67, Dschang, Cameroon;2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People''s Republic of China |
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| Abstract: | ![]()
Two new cycloartane-type triterpenoids, glaucartanoic acids A (1) and B (2), together with five known compounds were isolated from the fruits of Caloncoba glauca. Their structures were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques, by chemical evidence and by comparison with literature data. The new compounds were evaluated for their in vitro cytotoxicity against five human cancer cell lines. |
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