Alkaloids from Galanthus rizehensis |
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| Authors: | Buket Bozkurt Sarikaya Gulen Irem Kaya Mustafa Ali Onur Francesc Viladomat Carles Codina Jaume Bastida Nehir Unver Somer |
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| Institution: | 1. Department of Pharmacognosy, Faculty of Pharmacy, Ege University, Bornova, 35100 Izmir, Turkey;2. Departament de Productes Naturals, Biologia Vegetal I Edafologia, Facultat de Farmàcia, Universitat de Barcelona, Av. Diagonal 643, 08028 Barcelona, Spain |
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| Abstract: | Two new Amaryllidaceae alkaloid N-oxides, incartine N-oxide (1) and lycorine N-oxide (2) together with one β-carboline alkaloid, 1-acetyl-β-carboline (3) and six known alkaloids namely, incartine (4), N-trans feruloyltyramine (5), lycorine (6), O-methylnorbelladine (7), vittatine (8) and 11-hydroxyvittatine (9) were isolated from Galanthus rizehensis Stern (Amaryllidaceae). The structures of the alkaloids were elucidated by spectroscopic analyses (UV, IR, MS, 1D and 2D NMR). Acetylcholinesterase inhibitory activity potentials of the compounds were also determined. |
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